Nilai normal: <16 ng / mL [SI: <16 uL, trimester ketiga kehamilan, maksimum 550 ng / ml [Sl: 550 uL]).

Peningkatan: Hepatoma (karsinoma hepatoseluler), tumor testis (karsinoma embrional, teratoma ganas, yolk sac tumor), cacat tabung saraf (dalam serum ibu [spina bifida, anencephaly, myelomeningocele]), kematian janin, kehamilan multipel, ataksia-telangiectasia, beberapa kasus penyakit hati jinak (sirosis alkoholik, hepatitis).

Penurunan: trisomi 21 (sindrom Down) dalam serum ibu.  ALT (Alanin aminotransferase, ALAT)

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